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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1A
All Species:
15.15
Human Site:
T916
Identified Species:
25.64
UniProt:
O15047
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15047
NP_055527.1
1707
186034
T916
E
K
R
P
R
P
S
T
P
A
E
E
D
E
D
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
T916
E
K
R
P
R
P
S
T
P
A
E
E
D
E
D
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_848999
1330
145541
S619
A
A
E
P
L
P
S
S
S
V
S
G
E
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
T976
Q
K
R
L
R
P
S
T
S
V
D
E
E
D
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506028
1287
141359
A576
M
V
Q
E
E
P
V
A
P
A
G
P
D
R
E
Chicken
Gallus gallus
Q5F3P8
2008
223067
T969
Q
K
R
I
R
P
S
T
S
V
D
D
E
D
E
Frog
Xenopus laevis
Q66J90
1938
216239
H934
Q
K
R
I
R
P
S
H
S
V
D
D
E
D
E
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
S972
G
K
E
E
S
S
L
S
D
H
E
E
E
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
P884
S
K
I
K
G
P
V
P
I
Q
E
S
D
S
K
Honey Bee
Apis mellifera
XP_395451
1406
159180
A695
D
S
R
Q
S
D
H
A
D
T
E
L
I
G
S
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
L796
F
A
A
L
D
E
K
L
H
L
K
A
I
A
D
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
N1123
P
G
Q
L
N
P
F
N
S
P
D
M
L
P
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38827
1080
123894
K369
Q
E
N
L
K
K
A
K
E
K
E
A
E
N
E
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
Q602
D
I
E
E
E
K
K
Q
R
A
K
N
L
D
P
Conservation
Percent
Protein Identity:
100
99.5
N.A.
73.2
N.A.
37
N.A.
N.A.
27.7
34.5
34.1
36.7
N.A.
25.6
24.6
20.9
23.7
Protein Similarity:
100
99.5
N.A.
74.7
N.A.
49.5
N.A.
N.A.
38.7
47.5
48.6
50.7
N.A.
41.3
39.6
35.8
39.2
P-Site Identity:
100
100
N.A.
26.6
N.A.
46.6
N.A.
N.A.
26.6
40
33.3
20
N.A.
26.6
13.3
6.6
6.6
P-Site Similarity:
100
100
N.A.
40
N.A.
80
N.A.
N.A.
40
80
73.3
33.3
N.A.
26.6
20
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.7
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
33.8
36.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
0
0
0
8
15
0
29
0
15
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
0
0
0
8
8
0
0
15
0
29
15
29
29
22
% D
% Glu:
15
8
22
22
15
8
0
0
8
0
43
29
43
22
36
% E
% Phe:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% F
% Gly:
8
8
0
0
8
0
0
0
0
0
8
8
0
8
0
% G
% His:
0
0
0
0
0
0
8
8
8
8
0
0
0
0
0
% H
% Ile:
0
8
8
15
0
0
0
0
8
0
0
0
15
0
0
% I
% Lys:
0
50
0
8
8
15
15
8
0
8
15
0
0
0
8
% K
% Leu:
0
0
0
29
8
0
8
8
0
8
0
8
15
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
8
0
0
0
8
0
8
0
% N
% Pro:
8
0
0
22
0
65
0
8
22
8
0
8
0
15
8
% P
% Gln:
29
0
15
8
0
0
0
8
0
8
0
0
0
0
0
% Q
% Arg:
0
0
43
0
36
0
0
0
8
0
0
0
0
8
0
% R
% Ser:
8
8
0
0
15
8
43
15
36
0
8
8
0
8
8
% S
% Thr:
0
0
0
0
0
0
0
29
0
8
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
15
0
0
29
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _